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  a therapeutic agent for milk fever (replacement fluid by IV injection)
samu CㆍOㆍP injection
Category General Therapeutics
Product type Injectable solution
Target animal(s) Swine, Bovine, Companion animal, Others
Packing 500ml vial

Composition
 
Calcium Gluconate …………………………………………… 25%
Calcium Hypophosphite ……………………………………… 2.25%
Magnesium Chloride ………………………………………… 3%
Dextrose ………………………………………………………… 5%


Feature and Benefits
 
Calcium is indispensible not only for the formation and growth of bones, but also for the normal functioning of both neuromuscular system and heart, blood clotting and for many other processes. Calcium deficiency causes increased neuromuscular sensitivity which may lead to tetany.
When applied parenterally Calcium stimulates the heart functioning and entire blood circulation. By reducing the permeability of cells and blood vessels it reduces extravasation and favorably influences allergic and toxic conditions and inflammatory processes in the skin and mucous membranes. By reducing neuromuscular sensitivity Calcium also removes tetanic symptoms.
samu COP injection, a calcium-combination therapy, has Ca-Gluconate which is not stimulative and safe as a main ingredient. This product is a sterile aqueous solution prescribed to treat Calcium deficiency. And being reinforced with Phosphorus, Magnesium, and Dextrose, it has outstanding efficacy on hypomagnesemia, hypophosphatemia, and also on carbohydrate-supply.



Indications
 
For use as an aid in the treatment of hypocalcemia (parturient paresis, milk fever), hypomagnesemia (grass tetany), and other conditions associated with Calcium, Phosphorus and Magnesium deficiencies such as ketosis, parturient paresis, and various toxic symptoms in livestock.


Dosage and Use
 
The solution should be warmed to body temperature and admistered slowly and intravenously as follows. If necessary, may be repeated after 4~5 hours.
Cattle : 500mL per 450kg of body weight
Swine, Sheep : 50~100mL / a dose
Dog : 10~20mL / a dose
Generally it is recommended to inject into intravein. However, if necessary, it is possible to administer a half of usual dose for intramuscular, subcutaneous or abdominal injection in order to maintain calcium-concentration in blood for long period.


Precaution(s) and others